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Acute liver failure can cause various toxins to circulate in the bloodstream. To remove these toxins, several kinds of artificial liver support systems (ALSSs) can be used, such as plasma exchange (PE), high-flow hemodialysis (HD), high-volume hemofiltration (HF), high-flow volume hemodiafiltration (HDF), and albumin dialysis therapies. Plasma exchange with dialysis (PED) is a blood-purification therapy in which simple PE is performed using a selective membrane plasma separator while the dialysate flows outside the hollow fibers of the plasma separator [1–4]. This method is a useful ALSS for the removal of both water-soluble and albumin-bound toxins and has a reasonable cost.

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Plasma Exchange with Dialysis (PED)

  • 章节

  • 发表日期：

    2026年

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  • Hajime Nakae

摘要

Acute liver failure can cause various toxins to circulate in the bloodstream. To remove these toxins, several kinds of artificial liver support systems (ALSSs) can be used, such as plasma exchange (PE), high-flow hemodialysis (HD), high-volume hemofiltration (HF), high-flow volume hemodiafiltration (HDF), and albumin dialysis therapies. Plasma exchange with dialysis (PED) is a blood-purification therapy in which simple PE is performed using a selective membrane plasma separator while the dialysate flows outside the hollow fibers of the plasma separator [1–4]. This method is a useful ALSS for the removal of both water-soluble and albumin-bound toxins and has a reasonable cost.