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Low-density lipoprotein (LDL), with a specific gravity of 1.019–1.063 g/mL and a particle size of 19–22 nm, is recognized as a causative molecule of atherosclerosis. Foam cells, formed by macrophages that accumulate modified LDL cholesterol (LDL-C), like oxidized LDL-C, promote atherosclerosis. In addition, hyperlipidemia is a risk factor for myocardial infarction.

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Low-Density Lipoprotein Apheresis

  • 章节

  • 发表日期：

    2026年

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  • Sumi Hidaka,
  • Shuzo Kobayashi

摘要

Low-density lipoprotein (LDL), with a specific gravity of 1.019–1.063 g/mL and a particle size of 19–22 nm, is recognized as a causative molecule of atherosclerosis. Foam cells, formed by macrophages that accumulate modified LDL cholesterol (LDL-C), like oxidized LDL-C, promote atherosclerosis. In addition, hyperlipidemia is a risk factor for myocardial infarction.