The demand of residential units in Bangkok is increasing due to the increased population and migration. More houses and buildings are demolished, and new units are built to accommodate the increased demand. This results in high construction and demolition (C&D) waste. This study utilizes multiple linear regression to estimate the amount of C&D waste for detached houses in Bangkok. Key economic-related factors, including the annual number of constructions permits, number of detached houses, population, long-term credits for house loans, average monthly income, average material’s price index, and land cost are used in the analysis. The results reveal that construction waste tends to decrease due to less demand for detached houses. In contrast, the demolition waste is expected to increase as more outdated houses are demolished to build new and modern living units like condominiums. The total C&D waste of detached houses is expected to reach 10.6 million tons in 2030. The government and related stakeholders may use the study results to plan for an effective waste management to minimize the environmental impacts in the future.