This study examines the impact of Entrepreneurship Education (EE) within educational institutions on the Entrepreneurial Intentions (EI) of university students in the Southeast region. Using a quantitative approach with SmartPLS software, the survey results demonstrate a positive influence of EE on EI. Additionally, the study highlights the mediating roles of Entrepreneurial Self-Efficacy (ESE) and Entrepreneurial Attitude (EA) in the relationship between EE and EI. Furthermore, it investigates the moderating effect of Entrepreneurial Motivation (EM) on the relationship between EI and Entrepreneurial Behavior (EB). The findings not only affirm the significance of entrepreneurship education but also provide a scientific foundation for developing more effective entrepreneurship programs, particularly focused on enhancing students’ confidence, knowledge, and attitudes. This research is crucial for promoting sustainable development by fostering a new generation of entrepreneurs who are equipped to innovate and contribute positively to the economy. Future research directions may expand the scope of this study, offering a more comprehensive analysis and assessing the long-term impacts of entrepreneurship education on sustainable practices in business.