Evaluation of vitiligo can be aided by noninvasive diagnostic methods, which help confirm the diagnosis, assess disease activity, evaluate treatment response, and support research efforts. Commonly used noninvasive methods include dermoscopy, reflectance confocal microscopy, Wood’s lamp examination, and digital imaging, with or without assessment by artificial intelligence or computer software. Less common methods include colorimetry, spectrophotometry, digital planimetry, and infrared or ultraviolet light photography. The latest methods include third harmonic generation microscopy, multiphoton microscopy, and optical coherence tomography. The Wood’s lamp is the most commonly used noninvasive diagnostic tool due to its affordability, wide availability, and ease of use. Dermoscopy has gained popularity because of its portability, ease of image capture and storage, and the extensive published literature supporting its use. However, dermoscopy requires expertise, has a slow learning curve, and the cost of a dermoscope is high. Reflectance confocal microscopy is much more expensive than dermoscopy but offers better histopathological and disease activity correlation. It can also be used in combination with other methods. Additionally, various imaging techniques have been developed that can be used alongside computer software or artificial intelligence-based applications.