Polymyxin B is a cationic branched cyclic decapeptide isolated from the aerobic gram-positive rod Bacillus polymyxa. In dermatology, polymyxin B is used topically in combination with bacitracin and neomycin to broaden coverage against gram-negative bacteria, especially Pseudomonas aeruginosa.

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Polymyxin B

  • Aditya Kumar Bubna

摘要

Polymyxin B is a cationic branched cyclic decapeptide isolated from the aerobic gram-positive rod Bacillus polymyxa. In dermatology, polymyxin B is used topically in combination with bacitracin and neomycin to broaden coverage against gram-negative bacteria, especially Pseudomonas aeruginosa.