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This work presents an analytical solution for the current density or diffusion flux of an amperometric biosensor which simulates the experimental work of Romero et al. (2012). A diffusion equation-based model which involves nonlinearity relating enzyme kinetics has been discussed widely. Diffusion and their reactions within the enzyme matrix (sandwich type), an amperometric biosensor for the steady-state condition has been discussed. A near frame of solution of concentrations corresponding to the biosensor current for the steady-state condition is derived using the modified Adomian decomposition method (MADM). Comparisons have been done among the analytical, experimental, and numerical solutions. The obtained analytical current curve fits very well with the experimental current curves.

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Comparison of Analytical Solution of Current Density with Its Experimental Result of an (Sandwich-Type) Amperometric Biosensor

  • 会议论文

  • 发表日期：

    2026年

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  • T. Praveen,
  • M. Veeramuni,
  • K. Saravanakumar

摘要

This work presents an analytical solution for the current density or diffusion flux of an amperometric biosensor which simulates the experimental work of Romero et al. (2012). A diffusion equation-based model which involves nonlinearity relating enzyme kinetics has been discussed widely. Diffusion and their reactions within the enzyme matrix (sandwich type), an amperometric biosensor for the steady-state condition has been discussed. A near frame of solution of concentrations corresponding to the biosensor current for the steady-state condition is derived using the modified Adomian decomposition method (MADM). Comparisons have been done among the analytical, experimental, and numerical solutions. The obtained analytical current curve fits very well with the experimental current curves.