Due to the unique structure and operating principle, sleeve control valves are crucial in nuclear power fields, particularly in applications requiring precise flow and pressure control. When fluid goes through a sleeve control valve, pressure pulsation is generated, resulting in cyclic forces acting on the valve core. The cyclic forces can cause issues such as vibration or wear, which have a negative impact on the valve’s stability and safety. Under cavitating flow conditions, these detrimental effects may be more severe. Therefore, this study aims to investigate the pressure pulsation of a sleeve control valve under cavitating flow conditions. The study focuses on a sleeve valve and analyzes the flow characteristics under different conditions. Four conditions are chosen in this paper: no cavitation, incipient cavitation, mild cavitation, and intense cavitation. Transient numerical simulations are used to explore the time and frequency characteristics of cyclic forces acting on the valve core under these conditions. By analyzing the central frequency and amplitude of cyclic forces, pressure pulsation characteristics under cavitating flow can be investigated. This research provides a reference for future studies of pressure pulsation characteristics of sleeve control valves, which is conducive to improving the stability and safety of valves.