Myths are often dismissed as unimportant and therefore irrelevant. Such quick dismissal however fails to appreciate what scholarly research reveals about myths. Scholarly studies of myths go back centuries in human history, and have shed light on their nature, their meanings and role, their origins and their societal significance. Specifically, myths are said to be anchored in culture and serve as narrative forms with symbolic expression to a system of relationships between human and their universe. They fulfil the role of recording and validating social institutions, of exerting control over social and moral behavior, and serving as psychologically and socially stabilizing factor within society. Myths are also dynamic and assume diverse forms in different contexts. The focus of this chapter is on indigenous African myths as part of the African Indigenous Knowledge System, and therefore part of African cultural knowledge heritage. This is done with the view to explaining their historical role and nature is society as well as exploring the possible contribution they can make towards indigenization of education and curriculum in South Africa, including attendant challenges, following decades and centuries of subjugation under the colonial and apartheid control.