This paper proposes a RE102 simulation analysis method based on test data and the worst case model to solve the problem of military equipment RE102 simulation. The method is based on the board level RE102 test data of the equipment, and calculates the board level radiation coupling function based on the worst-case method, and deduces the contribution function of the interference source. On this basis, the radiation coupling function of the actual equipment is calculated based on the worst-case method, and its RE102 simulation is realized. The simulation results are in good agreement with the test results, which proves the effectiveness of the proposed method.