This study addresses the precision strike problem of high-speed vehicles subject to simultaneous field-of-view (FOV) and impact angle constraints by proposing an integrated guidance and control (IGC) strategy. The significant coupling effects between the guidance and control loops in the model are quantitatively analyzed by dynamic relative gain array (DRGA), which clarifies the importance of IGC design. Considering the dual angular constraints of the detection view field and the terminal impact, a novel FOV angle command is proposed to incorporate the constraint concerns into the IGC framework. Further with the help of a disturbance observer-based sliding mode controller to handle mismatched disturbances, thus enabling the precise impact at a specific angle. Stability is proven via Lyapunov analysis, which guarantees the asymptotic convergence of tracking errors. Numerical simulations demonstrate the effectiveness of the proposed method over conventional approach, achieving simultaneous constraint satisfaction and rapid convergence of the sliding surface under various operating conditions.