In the packaging and shipping industry, the efficient handling of cardboard box partitions is crucial for maintaining product integrity during transit. This article focuses on the conceptual design study of a corrugated cardboard box partition opener (2 × 2), which plays a pivotal role in creating compartments within a box to safeguard items from damage. Two conceptual designs were evaluated to automate the partition-opening process: concept A, involving a telescopic cylinder and linear pneumatic guided cylinder system, and concept B, utilizing a vertical cylinder for Z-axis movement along with a telescopic arrangement for corrugated partition handling. Through concept screening and scoring by referring to the reference, concept B emerged as the more viable solution due to its streamlined design and integration of both 2 × 2 opening and flat-type partitions into a single station. The calculations for force and torque requirements confirmed that the standard pneumatic components are sufficient for the task. The article concludes that adopting concept B will enhance operational efficiency, reduce complexity, and contribute to cost-effective and reliable handling processes, ultimately improving the overall supply chain performance.