The training and assessment of operators in nuclear power plants has always been the basis of ensuring nuclear power safety. The article proposes a concept of full-scope operation crew training system in digital nuclear power plant by combining system simulation technology with virtual reality technology, and completes the system design and function development. The research has solved a series of technical problems such as the data coupling between full-scope simulator and virtual scene and equipment, modeling and optimization of the 3D scene, the training and assessment model of full-scope operation crew. Through the use of the system, it can break the barrier of former training system, establish the full-scope operation crew training system of multi-position collaboration and multi-task collaboration, effectively promote the standardization of on-site behavior of the local operator, enhance the competency of operation and maintenance personnel, the system has high popularization and application value.