Obesity is a global health issue that increases the risk of various diseases and is also strongly associated with obstructive sleep apnea (OSA), with a significant increase in OSA risk linked to weight gain. Weight loss remains the key treatment for OSA, with approaches including diet control, exercise, medications, and surgical options. FDA-approved medications such as Orlistat, Phentermine-topiramate, and GLP-1 receptor agonists are effective for weight management. Bariatric endoscopic procedures like gastric balloon insertion and endoscopic sleeve gastroplasty offer minimally invasive alternatives to surgery. Bariatric surgery, particularly sleeve gastrectomy and Roux-en-Y gastric bypass, provides long-term weight loss and improvement of obesity-related comorbidities. However, some patients may still experience moderate-to-severe OSA, making combined airway and bariatric surgery (CABS) a promising solution for these individuals.

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Obesity, OSA, and Management

  • Keng-Hao Liu,
  • I-Wen Chen,
  • Wey-Ran Lin

摘要

Obesity is a global health issue that increases the risk of various diseases and is also strongly associated with obstructive sleep apnea (OSA), with a significant increase in OSA risk linked to weight gain. Weight loss remains the key treatment for OSA, with approaches including diet control, exercise, medications, and surgical options. FDA-approved medications such as Orlistat, Phentermine-topiramate, and GLP-1 receptor agonists are effective for weight management. Bariatric endoscopic procedures like gastric balloon insertion and endoscopic sleeve gastroplasty offer minimally invasive alternatives to surgery. Bariatric surgery, particularly sleeve gastrectomy and Roux-en-Y gastric bypass, provides long-term weight loss and improvement of obesity-related comorbidities. However, some patients may still experience moderate-to-severe OSA, making combined airway and bariatric surgery (CABS) a promising solution for these individuals.