Verify the necessary equipment, personnel, and preparations for performing double-balloon enteroscopy (DBE) for diagnosing and treating small bowel diseases. Transoral insertion requires fasting from solid food for 8–12 h and liquids for 4–6 h. For transanal insertion, bowel preparation similar to that for colonoscopy is needed. Given the prolonged nature of DBE, proper sedation and CO2 insufflation are recommended to enable deeper insertion and alleviate abdominal discomfort. To achieve deeper insertion, advance the DBE while creating a counterclockwise circular loop of the small bowel. Minimize force when advancing the enteroscope tip to reduce the risk of complications. When severe angulation or a complex loop of the small bowel occurs, the insertion force on the enteroscope shaft may not effectively transfer to the tip. Retracting the enteroscope with the overtube can help straighten the loop. Fluoroscopy may assist in confirming the scope’s rotation direction, straightening the proximal side, and determining the optimal point to stop shortening.