The internationalisation of higher education has important and different implications for quality assurance. As higher education internationalizes, quality assurance processes and standards need to adapt to continue to underpin confidence in qualifications. Processes of regionalisation and globalisation critically rest on the mobility of qualifications and skills, calling for harmonisation of education systems including their quality assurance. Quality assurance bodies themselves are internationalising their activities in response to growing international demand for international accreditation and reducing funding for their national activities. These three different dynamics, which could be referred to respectively as ‘quality assurance of internationalisation’, ‘harmonisation of quality assurance’, and ‘internationalisation of quality assurance’, raise specific challenges requiring specific solutions. This chapter aims to contribute to the development of these solutions, and ultimately to support fit-for-purpose quality assurance process in the context of internationalisation, by closely looking at the implications of internationalisation for quality assurance through the lenses of the above three strictly intertwined dynamics.