The escalating global demand for energy has spurred a critical search for alternative fuels to power internal combustion engines (ICEs). The formulation and application of gasoline surrogates in multi-point fuel injection (MPFI) spark ignition (SI) engines have gained significant interest in assessing their viability compared to commercial gasoline. Understanding the emission profiles of these surrogates is essential for optimizing engine performance and minimizing environmental impact. In MPFI SI engines, gasoline surrogates can alter combustion dynamics, thereby influencing the production of emissions such as carbon monoxide (CO), unburned hydrocarbons (HC), and nitrogen oxides (NOx). In this current study, the formulation of three gasoline surrogates and their emission analysis were carried out in an MPFI SI engine. The results demonstrated that both S-C and S-B surrogates exhibited lower CO and HC emissions compared to baseline gasoline operations. This improvement can be attributed to better combustion facilitated by the additional oxygen present in these surrogates.