The use of artificial intelligence with drones has rapidly expanded in various sectors, including military, agriculture, and commercial. However, its effectiveness in crime scene investigation is not well established. This article reviews current studies on the feasibility of AI and drones and examines challenges associated with using them in crime scene investigation. The goal is to inspire future research in this area. This research follows the Arksey and O’Malley framework and is updated by Joanna Briggs Institute Framework for Scoping Reviews methodology. 30 papers published from 2017 to 2024 were summarized, exploring the trend of AI and drone applications in crime scene investigation. The literature search covered Scopus, IEEE Xplore, and ScienceDirect, individual journals, gray literature, and Google. The uses of AI and drones in crime scene investigation are diverse, based on the articles discovered, AI and drone applications in crime scene investigation are grouped into three categories: (1) object detection, which demonstrated the biggest contribution, (2) photography and (3) real-time investigation. Though the last four years have seen a notable rise in the volume of papers on the application of drones and artificial intelligence, there hasn’t been much discussion about crime scene investigation, especially when identifying objects from the scene. More research has to be done on the uses of AI and drones, focusing on how these technologies may help investigators, particularly with object detection. With enough advancement, it is anticipated that the use of AI and drones will be more useful, especially when it comes to investigating crime scenes.