Considering the rapid depletion of non-renewable energy (e.g., fossil fuels), the development of new renewable energy sources has garnered significant attention from the world’s scientific community. Water splitting can serve as an alternative clean energy source to address this energy issue. 2D trichalcogenides are promising materials for Hydrogen evolution reaction (HER) and Oxygen evolution reaction (OER). Due to their unique properties like layered structure, more active sites, tunable structures, and high abundance on earth, they can be a potential electrocatalyst for water splitting. Hence, the various properties and electrocatalytic activity of these trichalcogenides for HER and OER will be covered in this chapter. Additionally, this chapter emphasizes the various synthesis methods and high catalytic activity observed when transition metals are exfoliated with 2D trichalcogenides. To date, trisulfides and triselenides are mostly used for water splitting from the chalcogen group. The challenges faced and how to overcome those obstacles is explored as well to ensure maximum application in various fields.