This chapter delves into the pivotal role of sustainability and corporate social responsibility (CSR) in shaping the future of airline tour operations. As environmental and social governance (ESG) becomes central to global travel strategies, airlines are increasingly required to align their business practices with the principles of ecological stewardship, ethical engagement, and community impact. This chapter examines how sustainability is operationalized through decarbonization strategies, sustainable aviation fuel (SAF) adoption, digital carbon tracking, and eco-certified tour packages. It further explores how CSR extends beyond environmental action to include fair labor practices, destination stewardship, and local community empowerment. Key areas of focus include the integration of science-based climate targets, airline participation in global frameworks like ICAO’s CORSIA and the UN Sustainable Development Goals (SDGs), and the use of AI and blockchain to ensure transparent environmental performance and reporting. The chapter presents real-world case studies from leading airlines such as Lufthansa, Delta, and Singapore Airlines, showcasing how these organizations embed sustainability into core operations from route planning and supply chain choices to passenger-facing carbon offset programs and green loyalty incentives. Finally, the chapter evaluates the long-term value of sustainability and CSR in enhancing brand reputation, regulatory compliance, investor confidence, and customer loyalty. It emphasizes the competitive advantage gained by airlines that proactively embrace their social and environmental responsibilities. Through a comprehensive framework of strategies, technologies, and ethical imperatives, this chapter provides a roadmap for future-ready airline tour operations grounded in accountability, innovation, and global citizenship.