Boundary layer flow control technology which is a significantly reduce the resistance method of surface/underwater transport equipment has been concerned by researchers at home and abroad. In this paper, a numerical simulation method of two-phase flow was used to study the drag reduction effect of ship controlled by blowing air jet flow. The researches show that the air blowing control on the bow underwater hull can effectively change the resistance characteristics of the ship. With the increase of blowing velocity, there were an obvious air isolation layers on both sides of the ship model, and the air separation flows phenomenon were appeared in the downstream of the flow field, which is conducive to reducing the friction resistance of the ship. Two mutually perpendicular velocities are applied to the blowing port to form a jet perpendicular to the ship surface at a 45°, thereby to affect the boundary layer of the ship surface. The blowing control velocity is not the greater the better, but there is an optimal value that have the best the drag reduction effect. Therefore, when the ship is sailing, the blowing control speed should be adjusted according to the sailing speed to achieve the optimal drag reduction effect.