Gardner’s theory of Multiple Intelligences provides a framework for understanding how humans learn. However, it has been challenged for encompassing a limited number of aspects. This study aims to extend the Multiple Intelligence profile by incorporating additional biological and psychological factors. Specifically, it examines the correlations between the Multiple Intelligence profile and six factors—age, gender, chronotype, sleep duration, illusion of competence, and imposter phenomenon—among adult learners aged 18–27, utilizing the Learning Meta-Learning dataset. Previous studies have associated these factors with some distinct intelligences, but they have not considered the Multiple Intelligence profile as a unified unit, as recommended by Gardner. Multinomial logistic regression is employed in this study to examine the correlations between these factors and the overall Multiple Intelligence profile. This study has identified significant correlations between the Multiple Intelligence profile and four factors, with age and sleep duration exhibiting the strongest correlations. In contrast, gender and chronotype do not exhibit any statistically significant relationship. These findings emphasize the importance of integrating only empirically supported factors into the enhanced Multiple Intelligence framework, thereby addressing the challenges and strengthening the theory’s explanatory power. Insights from this study will be valuable for teachers and self-learners in optimizing learning outcomes.