The human-tiger conflict in Sundarban—the world’s largest mangrove forest represents one of the most severe wild-life conflicts of all time that reflects a complex human-ecological risky interaction between humans and wildlife (Treves et al., 2003). Every year about 100–120 people fall prey to the Sundarbans tigers and as per official records reports around 3000 ‘tiger widows’ on the Indian side and about 1000 on the Bangladesh side who suffer ostracism and a life of seclusion. The life of the widows in the global south is an example of socio, cultural, and religious marginalization, physical, sexual, and gender discrimination, economic abuse, and exploitation due to the deep-rooted intertwined superstitious beliefs and socio-cultural stigma of the region and its people. The review is an endeavor to present the multifarious impact of human-tiger conflict on the widows and their children in the Sundarbans. Critical examination and future directions are outlined.