In order to accelerate the comprehensive reform and promote the high-quality development of higher education, this paper proposes a new type of integrated teaching reform method based on the characteristics of Fundamentals of Mechanical Manufacturing Technology course. Based on the OBE teaching concept, taking the course objectives, graduation requirements, project results, and student competence objectives as the main goal orientation, with project-based teaching as the main line and task carrier, integrating online and offline blended teaching means, an innovative project-based teaching method is constructed. The actual progressive teaching practice cases were used to demonstrate the specific implementation process and the implementation effect of the new teaching method. Practice has proved that the proposed integrated innovative project-based teaching reform model can guarantee the efficient and high-quality implementation of the course teaching process, promote the cultivation of high-quality research-oriented innovative talents with solid professional skills, and provide new energy for the cultivation and development of new productivity in the manufacturing industry.