The temporomandibular joint (TMJ) and craniomaxillofacial prostheses serve as critical approaches for reconstructing bone and joint defects in the craniomaxillofacial region. The fundamental basis for prosthesis design derives from anatomical characteristics, kinematic patterns, and biomechanical properties of the joint. These parameters guide the prosthesis design, material selection, and manufacturing processes. Subsequently, the prostheses undergo rigorous physicochemical performance testing to evaluate compliance with international standards, followed by sterilization and packaging. This developmental process requires iterative clinician-engineer collaboration and continuous refinement to ultimately develop TMJ and craniomaxillofacial prostheses that meet both anatomical compatibility and physiological functional requirements.