Management of Discoid Lupus Erythematosus (DLE)
摘要
Accurate diagnosis and effective management of discoid lupus erythematosus are critical to prevent irreversible disfigurement and potential progression to systemic lupus erythematosus (SLE). The management begins with a thorough clinical assessment and system screening. General management emphasizes strict photoprotection and supportive care. Topical therapies—including potent corticosteroids, calcineurin inhibitors, and retinoids—serve as the first-line treatment for localized disease. For extensive or refractory cases, systemic therapies such as antimalarials, corticosteroids, immunosuppressants, and biologics are employed. Surgical modalities, including excision and laser therapy, may be considered for residual scarring. Regular monitoring of disease activity and treatment-related adverse effects is essential to achieving optimal outcomes.