General rules of conduct in social spaces facilitate effective communication. With the advancement of technology, it has become crucial for us to imbibe etiquette for online interactions (chats, meetings, and video conferences). It is important to recognize the significance of privacy, to respect people’s time, and to keep the tone and manner civil. Ethical online behaviour can ensure healthy networking. One can create a lasting impression digitally by being respectful and refraining from confrontational or offensive language. Maintaining privacy in a safe digital environment has become a global concern. Thus, there’s an urgency to lay rules for institutional online interactions to avoid workplace harassment. Exercising discretion and caution can prevent oversharing. It keeps the personal information guarded. The age of social media requires drawing boundaries on digital platforms to avert obscenities and hostility. Resisting disrespectful comments and feedback with a positive attitude can set an example for others to follow. Always perform fact-checking before posting any information to counter fake news and online scams. Digital communication can establish inclusive spaces for all, especially those belonging to marginalized communities, if used judiciously. Chatting sites and web forums have witnessed a surge in hateful remarks in recent years. Promoting polite behaviour will generate a sense of safety among netizens. The workplace requires prompt and proper responses to emails with clarity. This, too, is necessary for effective digital communication. The thumb rule is to curb derogatory language and behave as you would in face-to-face interactions. The chapter deals with the importance of practicing netiquette, basic rules for safe online interaction, barriers to effective digital communication, and ways to overcome them.