Aortic dissection, the most common of the acute aortic syndrome, is a life-threatening condition that demands prompt diagnosis and management in the intensive care unit (ICU). It occurs when a tear in the intimal layer of the aorta allows blood to enter the medial layer, creating a false lumen that compromises blood flow and weakens the vessel wall. This can result in catastrophic complications such as aortic rupture, aortic regurgitation, myocardial ischemia, cardiac tamponade, acute stroke, malperfusion of critical organs, or death. Early identification and treatment are crucial to improve patient outcomes [1] [Ref: Algorithm 72.1].