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Acute liver failure (ALF) is a critical condition characterized by the rapid deterioration of liver function in patients without preexisting liver disease. This condition can progress rapidly and lead to life-threatening complications, including cerebral edema, coagulopathy, and multi-organ failure. The management of ALF in the intensive care unit (ICU) requires a systematic approach to stabilize the patient, prevent complications, and evaluate for potential liver transplantation. This chapter outlines a comprehensive approach to managing ALF, integrating the latest clinical guidelines and considerations [1, 2] [Ref: Algorithm 45.1].

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Approach to Acute Liver Failure in the ICU

  • 章节

  • 发表日期：

    2025年

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  • Shakti Bedanta Mishra,
  • Samir Samal,
  • Sagarika Panda

摘要

Acute liver failure (ALF) is a critical condition characterized by the rapid deterioration of liver function in patients without preexisting liver disease. This condition can progress rapidly and lead to life-threatening complications, including cerebral edema, coagulopathy, and multi-organ failure. The management of ALF in the intensive care unit (ICU) requires a systematic approach to stabilize the patient, prevent complications, and evaluate for potential liver transplantation. This chapter outlines a comprehensive approach to managing ALF, integrating the latest clinical guidelines and considerations [1, 2] [Ref: Algorithm 45.1].