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Cholangitis and cholecystitis are acute biliary conditions commonly encountered in critically ill patients, requiring prompt diagnosis and intervention to prevent significant morbidity and mortality. Acute cholangitis results from an infection of the biliary system, typically secondary to obstruction by stones or strictures. Cholecystitis refers to the inflammation of the gallbladder, often caused by gallstones obstructing the cystic duct. Both conditions can lead to life-threatening complications, including sepsis, organ failure, and death if left untreated. This chapter outlines the evidence-based management of these conditions, incorporating recent guidelines such as the 2024 IDSA (Infectious Diseases Society of America) Guidelines and the ASGE (American Society of Gastrointestinal Endoscopy) Guidelines for cholangitis [1, 2] [Ref: Algorithm 35.1].

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Approach to Cholangitis and Cholecystitis in the ICU

  • 章节

  • 发表日期：

    2025年

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  • Shakti Bedanta Mishra,
  • Samir Samal,
  • Sagarika Panda

摘要

Cholangitis and cholecystitis are acute biliary conditions commonly encountered in critically ill patients, requiring prompt diagnosis and intervention to prevent significant morbidity and mortality. Acute cholangitis results from an infection of the biliary system, typically secondary to obstruction by stones or strictures. Cholecystitis refers to the inflammation of the gallbladder, often caused by gallstones obstructing the cystic duct. Both conditions can lead to life-threatening complications, including sepsis, organ failure, and death if left untreated. This chapter outlines the evidence-based management of these conditions, incorporating recent guidelines such as the 2024 IDSA (Infectious Diseases Society of America) Guidelines and the ASGE (American Society of Gastrointestinal Endoscopy) Guidelines for cholangitis [1, 2] [Ref: Algorithm 35.1].