The field of antenna design has quickly evolved in recent years, driven by the ever-increasing demand in bandwidth, flexibility, gain, etc. for high-performance wireless communication systems. One such innovation in this field is the addition of metamaterial structures (such as metamaterial unit cell, metasurface, high impedance surfaces, etc.) in the design model of dielectric resonator antennas (DRAs) system. In this chapter, an overview of metamaterial-based DRAs, including their design guidelines, advantages, techniques of combination, and state of art, has been discussed. Various types of metamaterial structures that can be used in the design of these antennas and their contribution in the development of DRA-based efficient design are also explored. Finally, several case studies will be presented that demonstrate the effectiveness of metamaterial-based DRAs in real-world applications for current and future communication ecosystem.