This chapter explores the interplay between evidence-based practice and clinical intuition in shared decision-making in healthcare, particularly under conditions of uncertainty. It discusses the difficulties of communicating statistical evidence to patients and the influence of data availability and its relevance to individual patients. The authors argue that data-driven decision strategies are superior under stable conditions with reliable data, while intuitive strategies may be advantageous when information is uncertain or insufficient. It is emphasised that physicians should recognise and reflect on the learning environment in which they find themselves in order to improve their decision-making. The chapter concludes that a balance needs to be struck between the use of medical evidence and the selective application of clinical experience in shared decision-making, because uncertainty and intuition will remain essential components of clinical judgement.