Advances for powered prosthetic technology have demonstrated notable evolution for the approximate span of the past decade. Trends have been identified, such as the realization of sophisticated neural control through electromyograph (EMG) signalElectromyogram (EMG) analysis. Some of these capabilities have been supported by novel surgical techniques, such as the agonist–antagonist myoneural interface (AMI)Agonist-Antagonist Myoneural Interface (AMI). These research prototypes have been successfully applied for realizing continuous neural control, outdoor activities, such as rock climbing, and return to military service. Additionally, actuator configurations, such as incorporation of dual actuatorDual actuator, parallel elastic actuatorParallel elastic actuator, and variable transmission elastic actuatorVariable transmission elastic actuator strategies, have enabled unique adaptability and more biomimeticBiomimetic torque profiles during gait. Furthermore, efficient artificial intelligenceArtificial intelligence algorithms, such as fuzzy logicFuzzy logic, have been successfully implemented for terrain distinction. In summary, these evolutionary advances for powered prosthetic technology are examined from a system level perspective.