Transdisciplinary didactic concepts transcend disciplinary boundaries and address problem areas that cannot be solved by individual disciplines. The aim is to develop universal skills and overarching competencies in the areas of communication, cooperation, and collaboration. To this end, the perspectives, framework conditions, and challenges of transdisciplinary didactic concepts are presented, and possibilities for implementation are demonstrated using normalization process theory and specific guiding questions, which can be adapted to the particular learning groups, learning objectives, and learning content.