Healing requires contact! Traumatic or surgically created interfaces should come into contact with each other using suitable suture material, because only then will a restitutio ad integrum—a complete healing—result. Healing within wounds is a highly complex cascade involving the interplay of cell biological mechanisms such as inflammatory reactions, debridement, cell migration, and fibroblast activity. A wound is considered healed when it withstands all natural mechanical stresses and no inflammation is present. In the eye, a satisfactory result is always associated with the physical-optical, mechanical, or biological function. For example, a single corneal suture can completely seal a corneal incision and lead to healing, but make vision impossible due to suture-induced astigmatism. A poorly treated eyelid wound can lead to an ectropion and have serious effects on the corneal surface, up to and including blindness. The correct choice of suture material, as well as the proper handling of it, is particularly important for the treatment of wounds on the eye.