This chapter examines the use of Artificial Intelligence in initiating contact, a crucial step in the sales process. The initiation of contact is of central importance as it represents the first direct exchange with potential customers and thus lays the foundation for the further sales process. Subsequently, AI-based email campaigns and messages about product or service added value are explained. Other focal points are the AI-supported creation of video content and automated social media interactions. In addition, the use of AI-based chatbots and virtual assistants is discussed, followed by the automation of appointment scheduling. Finally, practical prompting tips for the use of ChatGPT and similar tools are presented.