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Hemorrhagic cystitis is a well-recognized complication in cancer patients and can be associated with increased morbidity and mortality. Its main etiologies include alkylating agent-chemotherapies, radiation therapy involving the pelvic area, and infections. Allogeneic stem cell transplant recipients are especially susceptible, due to exposure to conditioning chemotherapy and being at risk for BK virus-related infection, which can be associated with increased non-relapse mortality. In this chapter, we will discuss epidemiology, pathophysiology, treatment, and outcomes related to hemorrhagic cystitis in the cancer population with focus on BK CTL therapy.

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Hemorrhagic Cystitis in the Critically Ill Cancer Patient

  • 动态工具书词条

  • 发表日期：

    2026年

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  • Nada Youssef,
  • Chukuma Kalu,
  • Ala Abudayyeh,
  • Omar Mamlouk

摘要

Hemorrhagic cystitis is a well-recognized complication in cancer patients and can be associated with increased morbidity and mortality. Its main etiologies include alkylating agent-chemotherapies, radiation therapy involving the pelvic area, and infections. Allogeneic stem cell transplant recipients are especially susceptible, due to exposure to conditioning chemotherapy and being at risk for BK virus-related infection, which can be associated with increased non-relapse mortality. In this chapter, we will discuss epidemiology, pathophysiology, treatment, and outcomes related to hemorrhagic cystitis in the cancer population with focus on BK CTL therapy.