Anonychia-ectrodactyly is a rare congenital syndrome characterized by anonychia and ectrodactyly. It was first documented in the early twentieth century by Charteris (1918) and Hobbs (1935), who noted hereditary nail defects but overlooked associated limb abnormalities. The syndrome gained clearer definition in 1957 through a landmark study by Lees, Lawler, Renwick, and Thoday, who identified it in a large multigenerational family in Rotherham, Yorkshire. The disorder is congenital, with nonprogressive nail abnormalities and variable digital anomalies. While prevalence data are not explicitly provided, the familial clustering suggests rarity and it affects both sexes equally (Lees et al. 1957; Patiroğlu and Hasanoğlu 1989).