This chapter analyzes the development of the International Joseph A. Schumpeter Society's research agenda since 1986 and outlines a future program for a Schumpeterian transformational economics. It identifies six overlapping phases. Early work focuses on neo-Schumpeterian microeconomics and knowledge-based innovation analysis. Later phases address systems politics, industrial development, and the relationship between micro-processes and macro-outcomes. More recently, the focus has shifted to radical innovation, sustainability, and transformative change. To improve the understanding of those dimensions this chapter calls for a more in-depth, micro-based analysis of transformative structural change and the development of corresponding stylized empirical facts. Only on this basis can problem-appropriate policymaking to accompany transformative change succeed. The chapter concludes with remarks on the influence of the New Geopolitics on transformative patterns and processes.