This chapter presents a two-step science education study, on the topic of bacteria cultivation and hygiene. Among the many purposes of science education is to develop an understanding of health-related issues, of which hygiene is a central theme. Hygiene had been in focus for years in countries with poor water and sanitary systems, when it ended up in the spotlight around the whole world because of the outbreak of the COVID-19 pandemic in late 2019. Before the pandemic, in early 2018, we observed a Swedish fifth-grade science classroom when focusing on health in collaboration with a scientist specialised in the studies of bacteria (biochemist). The students’ immediate engagement in the bacteria topic was obvious, and it was apparent that the biochemist played a relevant role. Therefore, we decided to interview the teacher and a few of the students at the end of 2021 to find out how they reflected on the bacteria cultivation experience four years later. The aim of the study was to investigate the meaningfulness for the students and the teacher involved in a school project on bacteria cultivation in collaboration with a visiting scientist. The results showed that, according to both the teacher and the students, the project had influenced their thoughts and actions. They stated that the learning had been important and enjoyable, and they especially remembered the useful help and inspiration they received through the biochemist, who opened the hands-on part of the project.