This paper presents an interdisciplinary approach to the mathematical and ergonomic modeling of specialized workwear for gas-industry employees operating under extreme climatic conditions. The study is based on a survey of 430 field workers in the Bukhara region, Uzbekistan, aimed at identifying deficiencies in existing protective clothing and assessing ergonomic requirements. By analyzing anthropometric data, workplace conditions, and climate impacts, the proposed methodology integrates statistical evaluation with computer-aided design tools (Gemini CAD) to generate innovative workwear prototypes. The developed models account for thermal comfort, freedom of movement, and the use of auxiliary equipment, such as communication devices, thereby representing a multi-parameter optimization problem among safety, ergonomics, and productivity. Results demonstrate that mathematical modeling combined with ergonomic principles significantly improves both worker protection and operational efficiency. The approach reflects the broader potential of interdisciplinary modeling in solving complex engineering problems in occupational safety and industrial design.