The purpose of this chapter is to develop a legal ethics of the vulnerability of human beings given what happened in the COVID-19 pandemic crisis, by building up a legal and philosophical framework related to responsibility and human dignity concepts. Assessing the present alongside the burden of the past, however, requires a sensible view of the past aligned with the political equity of all human beings. The study examines a particular definition of human dignity from an ethical and legal point of view to advocate for the value and principle of responsibility as an epistemic tool to rethink the vulnerability of human beings. The role of this legal ethics is analyzed in the face of changes in medical ethics and the concepts of suffering and compassion for vulnerable people.