This volume compiles original research from global online roundtables organized by Juris North and Yale’s Academics Stand Against Poverty (ASAP) in 2020, amid the COVID-19 pandemic. Featuring multidimensional perspectives from scholars and activists across continents—including Argentina, China, Brazil, the US, UK, Italy, Spain, and the Netherlands—it addresses crises through a lens of pluralism, examining human dignity and climate change as interconnected themes exacerbated by the pandemic. The book critiques unidimensional approaches to global issues like pandemics, territorial disputes, terrorism, trafficking, and environmental degradation, advocating a multidimensional approach that encompasses the “pluralism of pluralisms” characteristic of crises to foster cooperative, effective solutions without eroding sovereignty. Part I explores the vulnerabilities of human dignity in health emergencies, Indigenous rights, and ethical responsibility, highlighting inequalities in marginalized groups. Part II analyzes climate governance issues, ranging from regulating greenhouse gases in the US and Brazil to BRICS responses and community innovations in water management amid COVID-19 disruptions. Dedicated responses to these contributions synthesize lessons for the development of multiscalar, equitable strategies, bridging local actions and global justice to protect vulnerable populations and promote sustainable recovery in a polycrisis era.