This study investigates and tests the role of online shopping intention in mediating the relationship between trust, online shopping attitude, and online shopping knowledge on online shopping behavior. By testing the regression relationship between these five constructs, it will be possible to find out how to improve online shopping behavior in the e-commerce industry in Indonesia. The selected sample used 247 people who usually shop via e-commerce. Data were collected by distributing questionnaires about the five constructs via Google Forms. This study used Structural Equation Modeling (SEM) with Smart PLS 4 for data analysis. The findings showed that trust, online shopping attitude, and online shopping knowledge have positive effects on online shopping intention. Furthermore, online shopping intention has a positive effect on online shopping behavior. Thus, online shopping intention can mediate the relationship between trust, online shopping attitude, and online shopping knowledge with online shopping behavior. Research findings also prove that online shopping attitudes cannot directly improve online shopping behavior. Online shopping attitudes can improve online shopping behavior by increasing online shopping intention.