Most of the Bronze Age knives from the Volga-Ural region had wooden handles, which almost never survive to this day. Sometimes only traces of wood on the knife handle remain from the wooden handles of such knives. In isolated cases, there are Bronze Age knives with bone and antler handles, which are much better preserved than wooden ones. In practice, such knives with horn and bone handles have a trapezoidal handle in plan, expanding towards the blade. In knives with horn handles, the stem of the knife was inserted into a narrow slot cut in the lower part of the handle. An interesting example of such a product is a knife with an antler handle, which was found in 1988 during the excavation of Kurgan 11 of the Bolshekaraganskiy cemetery under the direction of Sergei Botalov. This knife is part of the museum collection of the Museum of Archaeology and Ethnography of the Chelyabinsk State University. The stem of this knife is hidden by an antler handle and was studied using X-ray. It was found that the object belongs to the type of knife with a dagger-shaped blade and a stop for the handle, the stem of the knife ends in a rhombic pommel. The composition of the metal of this knife was determined by X-ray fluorescence analysis. It was found that the knife was made of arsenic copper with an admixture of nickel. The stem of the knife is firmly inserted into a groove cut in the handle. The studied knife was attributed to the Sintashta culture. The closest analogies to the design of the handle of this knife were found in burials of archaeological sites of the Potapovka cultural type, located in the Middle Volga region.