This chapter analyses a case study of deforestation and climate-related migration among indigenous and quilombola women in the Brazilian Amazon. It adopts an intersectional approach to vulnerabilities arising from gender, ethnicity and socio-economic factors and is framed within the paradigms of political ecology and decolonial feminism. The chapter contextualises this within a historical legacy of colonialism, agricultural expansion and extractivist policies that have accelerated environmental degradation since the Bolsonaro era. It examines how forest loss intensifies climate risks, affecting food security, territorial sovereignty and cultural reproduction. These risks have a differential impact on communities such as the Yanomami and Quilombola. The chapter identifies adaptive strategies, including resistance networks, sustainable agroforestry and legal advocacy, which empower women as epistemic agents in defending territories. However, it also addresses challenges such as political resistance, financial barriers and cultural obstacles that perpetuate marginalisation. The synthesis interprets these findings within a Latin American context and compares them with cases from the Andes and Central America to highlight similarities in intersectional discrimination. This contributes to debates on environmental justice and proposes inclusive policies that integrate Afro-descendant and indigenous epistemologies to foster equitable resilience in scenarios of global climate crisis.