Virtual Reality (VR) and Additive Manufacturing (AM) are transforming modern engineering education, especially in biomedical engineering fields where precision, customization, and collaboration across disciplines are essential. This paper introduces a process-focused framework that combines A-Frame, an open-source WebXR platform for immersive, browser-based simulations, with CALLME, an AI-supported educational tool. The integrated system enables students to explore and analyze every phase of the AM process, modeling, slicing, fabrication, and inspection, within a VR laboratory directly connected to CALLME’s adaptive analytics. The aim is to enhance the understanding of AM concepts through interactive digital twins, real-time feedback on parameters, and measurable learning outcomes. This approach promotes open, scalable, and data-driven education aligned with the human-centric principles of Industry 5.0. The achieved outcomes of the proposed framework include: (i) a structured, process-oriented representation of the complete additive manufacturing workflow in an immersive VR environment; (ii) real-time coupling of learner interactions with learning analytics, enabling objective observation of parameter exploration and decision-making strategies; and (iii) improved conceptual understanding of cause–effect relationships in AM processes through immediate visual feedback and adaptive learning paths.