Assistive technology is widely used by visually impaired and blind individuals, who rely mainly on the braille system for communication, reading, and writing in their daily life. Hence, the importance of developing and designing braille self-learning systems to facilitate independent learning, which will save time, effort, and cost, is a necessity. The system could be a primary tool or act as an aid tool during the learning process. This paper aims to reveal the features, deficiencies, needs, and challenges of such systems in order to improve and develop high-quality braille self-learning systems. The research review identified several braille self-learning systems; online systems, standalone device systems, computer-based systems, and smartphone-based systems. The researchers also provided recommendations for researchers and developers to achieve superior braille self-learning systems and applications to meet the targeted individuals’ needs.