Scholarlink

Many treatment protocols in oncology lead to manifest osteoporosis. Irradiation causes local atrophy of the bone and bone marrow due to the toxic effects on bone and bone marrow cells, while chemotherapy and hormone therapy induce systemic rarefaction of both trabecular and cortical bones. Moreover, these iatrogenic effects may even be increased by a direct effect on the bone of the tumour itself, which could well have preceded the deleterious effects of the therapy.

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Tumour-Therapy-Induced Osteoporosis

  • 章节

  • 发表日期：

    2026年

查看全文
  • Reiner Bartl,
  • Christoph Bartl

摘要

Many treatment protocols in oncology lead to manifest osteoporosis. Irradiation causes local atrophy of the bone and bone marrow due to the toxic effects on bone and bone marrow cells, while chemotherapy and hormone therapy induce systemic rarefaction of both trabecular and cortical bones. Moreover, these iatrogenic effects may even be increased by a direct effect on the bone of the tumour itself, which could well have preceded the deleterious effects of the therapy.