This chapter of this book builds on the foundations laid in the previous chapters and provides a detailed examination of the human rights and environmental responsibilities of companies in different contexts, with a particular focus on the HRDD responsibilities of different corporate actors. This chapter moves from the broader examination of corporate responsibility in Chaps. 2 and 3 to a more focused discussion of the tailored responsibilities of specific actors illuminated by the OECD case law. This chapter examines the critical role of various (corporate) actors, including MNEs with extensive global operations, financial institutions (FIs), state-owned enterprises (SOEs), and even non-profit organisations (NPOs), whose actions and decisions can have a significant impact on rights holders in economic activities (see Fig. 4.1). It is important to note that, although suppliers, technological companies, and audit and consultancy firms were coded in the CSA of the OECD case law under the different corporate actors’ responsibilities, their low numbers and lack of substantial analysis meant they were not examined in detail in this book.